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Structured Review

Charles River Laboratories human cell microarray platform
Human Cell Microarray Platform, supplied by Charles River Laboratories, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/human+cell+microarray+platform/human+cell+microarray/pm39871795-209-16-15
Average 90 stars, based on 1 article reviews
human cell microarray platform - by Bioz Stars, 2026-09
90/100 stars

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Related Articles

Construct:

Article Title: Applications of Cell-Based Protein Array Technology to Preclinical Safety Assessment of Biological Products.
Article Snippet: Off-target evaluation is essential in preclinical safety assessments of novel biotherapeutics, supporting lead molecule selection, endpoint selection in toxicology studies, and regulatory requirements for first-in-human trials.. Off-target interaction of a therapeutic antibody and antibody derivatives has been historically assessed via the Tissue Cross-Reactivity (TCR) study, in which the candidate molecule is used as a reagent in immunohistochemistry (IHC) to assess binding of the candidate molecule to a panel of human tissue sections.. The TCR approach is limited by the performance of the therapeutic as an IHC reagent, which is often suboptimal to outright infeasible.

Microarray:

Article Title: Applications of Cell-Based Protein Array Technology to Preclinical Safety Assessment of Biological Products.
Article Snippet: Off-target evaluation is essential in preclinical safety assessments of novel biotherapeutics, supporting lead molecule selection, endpoint selection in toxicology studies, and regulatory requirements for first-in-human trials.. Off-target interaction of a therapeutic antibody and antibody derivatives has been historically assessed via the Tissue Cross-Reactivity (TCR) study, in which the candidate molecule is used as a reagent in immunohistochemistry (IHC) to assess binding of the candidate molecule to a panel of human tissue sections.. The TCR approach is limited by the performance of the therapeutic as an IHC reagent, which is often suboptimal to outright infeasible.



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